Long-term effects of testicular cancer treatment and implications for follow-up
نویسندگان
چکیده
Samenvatting Testiskanker is goed te behandelen. De vijfjaarsoverleving momenteel > 90%. wordt meestal vóór het 40e jaar gediagnosticeerd, en patiënten kunnen na een succesvolle behandeling nog 40 tot 50 leven. Er echter verhoogd risico op langdurige late effecten van deze behandeling. Tweede primaire maligniteiten hart- vaatziekten zijn daarvan de meest voorkomende potentieel levensbedreigende. Andere nefrotoxiciteit, neurotoxiciteit, verminderde vruchtbaarheid, hypogonadisme, chronische vermoeidheid psychosociale problemen. Over onderliggende mechanismen genetische gevoeligheid voor verschillende bijwerkingen weinig bekend, waardoor niet mogelijk om met hoog bepaalde identificeren. Wij presenteren huidige stand zaken betreffende somatische langetermijneffecten formuleren aanbevelingen algemene medische evaluaties, die moeten beginnen bij start doorgaan voltooien follow-up.
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ژورنال
عنوان ژورنال: Tijdschrift voor urologie
سال: 2023
ISSN: ['2211-3037', '2211-4718']
DOI: https://doi.org/10.1007/s13629-023-00408-y